… in the Minneapolis Star Tribune notes that the most charitable description of what’s been going on at the clubby University of Minnesota medical school would be “bizarre.”
Saturday, February 19, 2011
A banner reading "Corporate Criminals Run Brown" appeared on Wayland Arch facing Wriston Quadrangle Friday evening
the Corporate University
The Brown and Minnesota Examples
The Brown and Minnesota Examples
Michael McNabb has nicely laid out the current situation at the University of Minnesota with respect to corporatization with his excellent series: University Inc and University Inc, Part II.
There are further consequences of corporatization which Jennifer Washburn has examined in her excellent article in in Academe, the magazine of the American Association of University Professors
In summary, she writes:
Commercial threats on campus have mounted—from industry control of research and corporate ghostwriting to restrictive sponsored-research agreements and intellectual property deals that place profits ahead of public health.
These threats to academic freedom should cause us to reconsider the meaning of the phrase academic freedom and to understand that similar threats led to the formation of the AAUP in 1915. Powerful corporate interests and wealthy donors wielded undue influence over academic institutions. Today we struggle with renewed threats to academic freedom by commercial interests. Should universities pursue truth or profits?
Washburn uses two cases from Brown University to illustrate her points. David Kern had his career ruined by crossing Brown's medical school administration who tried to bully him into retracting a scientific abstract. Kern's operation was shut down. Brown's medical school administration did appropriate waffling. (See Washburn for the sordid details.)
By contrast Washburn points out the treatment of the chairman of the department of psychiatry. Readers of this blog will recognize some eery similarities between this story and that of our own sorry University of Minnesota psychiatry department chair and Seroquel.
Martin Keller brought in a large amount of money (8.7+ million dollars) and was also the author of a puff piece, so-called Study 329, for the use of the anti-depressant Paxil in children. He then became famous for promoting the use of this drug “off-label” in children and adolescents. Shortly, however, the wheels started coming off his wagon. Elliot Sptizer went after GSK – Paxil's Daddy - for “repeated and persistent fraud” based in part on analysis of Kern's Study 329 raw data. GSK settled out of court.
Unfortunately for Kern, another group turned over the Paxil for children rock and looked again at the 320 data:
Psychiatrist Jon Jureidini of the University of Adelaide in Australia published a second independent analysis of Study 329’s raw data, which found “no significant difference” between Paxil and a sugar pill on any of the study’s eight prespecified outcome measure.
According to the Jureidini study, Keller and his co-authors also presented a distorted picture of Paxil’s safety by failing to report that eleven of the study’s patients taking Paxil had suffered serious adverse side effects (including eight cases of suicidal behavior and thinking).
[Cough, cough... Seroquel anyone? Dr. Schulz - Minnesota psychiatry chair and Seroquel shill?]
And of course there were ghostwriters in the sky:
Patient litigation related to the Paxil case also led to the release of internal company documents suggesting that Keller had violated traditional standards of “academic authorship” and “independent scholarship” by working closely with a GSK-paid ghostwriter.
And finally, the blow-off:
In 2008, shortly after Jureidini’s study appeared, David Egilman, a clinical associate professor in community health at Brown University, sent an e-mail to David Kertzer, Brown’s provost, requesting that the university investigate Keller’s possible role in scientific misconduct. In 2009, the Brown Daily Herald, the student newspaper, published an editorial questioning Brown’s apparent reluctance to hold Keller accountable. … Brown’s website currently states that Martin Keller is a full professor who “made major research contributions to the understanding and treatment of mood disorders.”
So what's going on here? Kern wanted to publish a paper about a topic that disturbed Microfibres, Inc. and after Brown failed to stop him, he was, as they say, let go.
Keller brought in a lot of money. It at least appears that he may have violated what I hope are ethical conduct standards at Brown. He is still there.
This is a pretty clear case of the conflict between the corporate university and academic freedom.
Dr Howard Brody has picked up on the Washburn article and give his views on the situation at Hooked:Ethics, Medicine and Pharma:
The university seems to have taken little of any action against Keller, their chair of psychiatry who brings in huge research grants from industry, despite his serious COI and his role in suppressing unfavorable data about the antidepressant Paxil in kids. Kern, by contrast, blew the whistle on corporate wrongdoing in the defense of public health, and saw his academic career destroyed as a consequence.
Dr. Brody also notes the implications for academic freedom:
Washburn diagnoses [these incidents] as a serious misunderstanding of the tradition of "academic freedom." University profs have today fallen into the trap of thinking that this as a purely individual right. Not so, argues Washburn.
As has the Minnesota Daily, the Brown Daily Herald – a student paper, has not been shy about pointing out the hypocrisy of university administration. The corporate affiliations of Brown members of the Governing Board as well as President Ruth Simmons membership on external boards such as Goldman Sachs are pointedly criticized in the article: Scandals Hound Corporation members.
At our place the membership of our former medical school dean on the Pepsi Cola board was also scandalous. Here Pepsi bought the prestige of having a medical school dean sitting on their corporate board. A company that makes products that rot children's teeth? And this behavior was defended by the Academic Health Center VP.
We seek truth and/or cash?
Recently a tiny little protest was mounted against the Brown corporation. As the Herald wrote in its Valentine's day report to the campus:
A banner reading "Corporate Criminals Run Brown" appeared on Wayland Arch facing Wriston Quadrangle Friday evening, a day before this weekend's meeting of the Corporation. Less than 24 hours later, the banner had been taken down. The banner included a small "TM" for "trademark" beside the word "Brown."
Universities seem to be into branding. Our brand at Minnesota is Driven to Discover. To discover what? Truth? Apparently the only limitation at Minnesota is whether an action is legal as demonstrated by the refusal of the Board of Regents to have an independent investigation of the Seroquel scandal. Such an investigation was requested by a large number of the University of Minnesota bioethics faculty. As the Minnesota Daily recently pointed out to the Board of Regents in an editorial entitled Regents Play Innocent:
The University seems to think that because it was not held liable in court for Markingson’s death, it did nothing wrong. This is false; it is a cynical excuse to keep corporate drug money flowing into the University.
The regents’ decision fundamentally undermines our mission: Supposedly, the University is “dedicated to … the search for truth.” But the letter makes it clear that corporate research cash is more important to the University than patient safety and transparency.
Refusing to set up an independent investigation is a willfully ignorant attempt to sweep the Markingson case under the rug and damages the integrity of the entire University.
Brown and Minnesota are quite different types of institutions, yet they both seem to have difficulties with the linkage between corporatization and the concept of academic freedom.
at 10:24 AM